Description: EcoCRM™ is CRM₁₉₇ produced as a soluble intracellular protein in E. coli. CRM₁₉₇ is genetically detoxified diphtheria toxin. Specifically, it has a single amino acid substitution (glycine52 to glutamic acid), which causes the ADPribosyltransferase activity…

IL-4, Interleukin-4, human: Human Interleukin-4 Interleukin-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival, and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of…

Description: Recombinant, HIS-tagged, purified Ebola virus (EBOV) matrix protein (VP24) is expressed in E. coli and the recombinant protein purified using FPLC. Size: 100 µg of protein is supplied in Tris buffered saline, at a concentration of 2.279 mg/mL. The theoretical molecular…

FGF-basic, Fibroblast Growth Factor-basic, human: Human Fibroblast Growth Factor-basic FGF basic (FGF-2, HBGF-2) is one of at least 22 mitogenic proteins of the FGF family, which show 35 - 60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are…

MIF, Migration Inhibitor Factor, human: Migration Inhibitory Factor (MIF) is a secreted protein without a cleavable signal sequence and is secreted via a specialized, non-classical pathway. It is secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.…

GMF beta, Glia Maturation Factor beta, murine (mouse): The glia maturation factor beta belongs to the actin-binding proteins ADF family, GMF subfamily. It contains an ADF-H domain, but the research of crystallography and NMR reveals that there are structures different between human and mouse…

The Bio Basic IL-36 Beta (153 a.a.), Murine (Mouse) is suitable for use in laboratory use only. It can be stored at a temperature of -15 to 20 degree C.

The Bio Basic IL-36 Beta (157 a.a.), Human is suitable for use in laboratory use only. It can be stored at a temperature of -15 to 20 degree C.

IL-36 beta (183 a.a.), murine (mouse): Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in the pathophysiology of several diseases. IL-36α, IL-36β, and IL-36γ (formerly IL-1F6, IL-1F8, and IL-1F9) are IL-1 family members that signal through…

CXCL3, CINC-2 beta, rat: The three GRO cDNAs encode 107 amino acid precursor proteins from which the N-terminal 34 amino acid residues are cleaved to generate the mature GROs. There are no potential N-linked glycosylation sites in the amino acid sequences. GRO expression is inducible by serum…

SDF-1 beta, CXCL12, rat: SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV…

FGF-acidic, Fibroblast Growth Factor-acidic, human: FGF acidic, also known as FGF-1 and endothelial cell growth factor, is a member of the FGF family of mitogenic peptides which currently is comprised of at least seven proteins which show 35-55% amino acid sequence conservation. FGF acidic and…

IP-10, CXCL10, human: IP-10 was originally identified as an IFN-γ-inducible gene in monocytes, fibroblasts, and endothelial cells. It has since been shown that IP-10 mRNA is also induced by LPS, IL-1β, TNF-α, IL-12 and viruses. Additional cell types that have been shown…

IL-3 beta, Interleukin-3-beta, rat: Interleukin-3 (IL-3) is a hematopoietic growth factor that promotes the survival, differentiation, and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced…

Description: Virus-like Particles (VLP’s) expressing recombinant Marburg (Musoke) virus (MMARV) glycoprotein (GP), nucleoprotein (NP), and matrix protein (VP40). These VLP’s are produced in Sf9 insect cells through infection with a recombinant baculovirus. Size: 1 mg of protein…

GMF beta, Glia Maturation Factor beta, human: GMF-β, a brain-specific protein that belongs to the actin-binding proteins (ADF) structural family. GMF-β appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the…

Description: Recombinant, full-length influenza hemagglutinin from virus strain A/JiangxiDonghu/346/2013 (H10N8). Recombinant hemagglutinin (rHA) is supplied as an affinity purified protein. rHA is produced in Sf9 insect cells using baculovirus for expression and is purified by FPLC. Size: 50…

IL-1 beta, Interleukin-1 beta, porcine: Interleukin-1 beta (IL-1β) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and…

BMP-4, Bone Morphogenetic Protein-4, human: Human BMP-4 is one of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor β (TGF-β) superfamily. BMPs were originally identified as protein regulators of cartilage and bone formation.…

IFN beta 1b, Interferon beta 1b, human: Human Interferon-β  Interferon-beta is one of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a cytokine with antiviral, antiproliferative, and…

GMF beta, rat: Glia Maturation Factor beta (GMF-β), a brain-specific protein that belongs to the actin-binding proteins (ADF) structural family. GMF-β appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the…

MIP-1 beta, CCL4, rat: Chemokine (C-C motif) ligand 4 encoded by the CCL4 gene, also known as macrophage inflammatory protein-1β (MIP-1β) is a CC chemokine with specificity for CCR5 receptors and it is a major HIV-suppressive factor produced by CD8+ T cells. In addition, it is a…

VEGF165, Vascular Endothelial Growth Factor 165, murine (mouse): VEGF was initially purified from media conditioned by normal bovine pituitary folliculo-stellate cells and by a variety of transformed cell lines as a mitogen specific for vascular endothelial cells. It was subsequently found to…

Description: : Purified, His-tagged Staphylococcus aureus PantonValentine Leukocidin (PVL) S subunit (LukS-PV). The theoretical molecular weight of the protein is 33,713 Daltons including the His-tag. Size: 100 ug of protein is supplied in PBS + 15% Glycerol at a concentration of 1 mg/mL.…

FGF-10, Fibroblast Growth Factor-10, human: KGF-2(also known as FGF-10) was originally identified from rat embryos by homology-based polymerase chain reaction. Human and mouse KGF-2 were subsequently cloned. The human KGF-2 cDNA encodes a 208 amino acid residue protein with a hydrophobic…

Protein G binds to the constant region of many species of immunoglobulin G. It can be used to detect, quantify and purify IgG antibodies and antibody/antigen complexes. Bio Basic Inc’s Recombinant Protein G contains only IgG binding domains. The albumin-binding domain as well as cell wall and…

GRO beta, CXCL2, rat: Rat CXCL2 also named CINC-3, belongs to the CXC chemokine family. It is encoded by the gene CXCL2 and shares 90 % amino acid sequence with CXCL1/GROα. It is member of the intercrine alpha (chemokine C-X-C) subfamily of chemokines. This chemokine is expressed by…

IL-1 beta, Interleukin-1 beta, monkey (rhesus macaque): IL-1 beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has similar if not…

Description: Recombinant, Influenza Hemagglutinin Full-Length Glycoprotein (rHA GP) from virus strain A/Hong Kong/33982/2009 (H9N2). Recombinant HA is supplied as an affinity purified protein. rHA is produced in Sf9 insect cells using baculovirus for expression and is purified by FPLC. Size: …

IFN alpha 1b, Interferon alpha 1b, human: At least 23 different variants of IFN-alpha are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-alpha subtypes possess a common conserved sequence…

MIP-2, CXCL2, murine (mouse): Macrophage Inflammatory Protein 2 (MIP-2) was originally identified as a heparin binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. Based on its protein and DNA sequences, MIP-2 is a member of the alpha (CXC)…

IL-12, Interleukin-12, human: Interleukin 12, also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a pleiotropic cytokine originally identified in the medium of activated human B lymphoblastoid cell lines. The p40 subunit of IL-12 has…