Synonyms: Quinine hemisulfate salt monohydrate; Quinine sulfate (2:1) (salt) dihydrate
Formula: C20H24N2O2 · 0.5H2O4S · H2O
Formula Weight: 391.47
CAS No.: 207671-44-1
Application: Use to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites, the toxicity of heme (FP)-complexes and to inhibit mitochondrial ATP-regulated potassium channel.
Biochem/physiol Actions: Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive, and hypoglycemic agent; alkaloid originally isolated from the Cinchona family of South American trees. Inhibits mitochondrial ATP-regulated potassium channel. Used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.