Biologically Active Small Molecules Products (435)

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  • Image of A66

    LKT Labs

    Inhibitor of p110a PI3K. It decreases viability of endometrial cancer cells and impairs glucose and insulin tolerance.

  • Image of 17-Allylaminogeldanamycin

    LKT Labs

    Geldanamycin derivative and HSP90 inhibitor. It induces apoptosis in cancer cells and inhibits replication of cytomegalovirus.

  • Image of A-779

    LKT Labs

    Mas antagonist that inhibits signaling by angiotensin (1-7), preventing vasodilation and insulin sensitization.

  • Image of 4-bromo-A23187

    LKT Labs

    Non-fluorescent halogenated A23187 analog and Ca2+ ionophore. It induces formation of endothelial microvesicles, increasing leakage of lactate dehydrogenase and decreasing cell viability. It also induces mast cell degranulation and stimulates the acros

  • Image of A23187 Ca-Mg

    LKT Labs

    Ca2+ ionophore. It induces formation of endothelial microvesicles, increasing leakage of lactate dehydrogenase and decreasing cell viability. It also induces mast cell degranulation and stimulates the acrosome reaction in spermatozoa.

  • Image of BAM-12P

    LKT Labs

    Bovine adrenal medulla 12 peptide (BAM-12P) is a cleavage product of proenkephalin that binds κ-opioid receptors (κORs). BAM-12P plays a role in antinociceptive signaling.

  • Image of BAM-22P

    LKT Labs

    κOR and µOR agonist and cleavage product of proenkephalin.

  • Image of Abacavir

    LKT Labs

    Guanosine analog and inhibitor of RT, guanylyl cyclase, and telomerase used to treat HIV infection.

  • Image of Abacavir Sulfate

    LKT Labs

    Guanosine analog and inhibitor of RT, guanylyl cyclase, and telomerase used to treat HIV infection.

  • Image of Abamectin

    LKT Labs

    F0F1-ATPase and adenine nucleotide translocator inhibitor and GABA receptor antagonist. It prevents mitochondrial respiration and decreases sperm count and motility.

  • Image of Abiraterone

    LKT Labs

    Progesterone derivative and Cyp17A1 inhibitor used to treat castration-resistant prostate cancer. It decreases androgen production and may inhibit eIF4F signaling.

  • Image of ABT-199

    LKT Labs

    BH3 mimetic and Bcl-2 inhibitor. It induces apoptosis in chronic lymphocytic leukemia cells

  • Image of ABT-263

    LKT Labs

    BH3 mimetic and inhibitor of Bcl-2, Bcl-?, and Bcl-xl. It enhances the efficacy of co-administered chemotherapeutics and inhibits proliferation of chronic lymphocytic leukemia cells.

  • Placeholder Image for ABT-737

    LKT Labs

    BH3 mimetic and inhibitor of Bcl-2, Bcl-xl, and Bcl-w. It inhibits growth of acute myelogenous leukemia cells and induces apoptosis and clearance in platelets.

  • Image of Acarbose

    LKT Labs

    a-Glucosidase inhibitor that decreases digestion of complex carbohydrates and prevents glucose absorption. It improves insulin sensitivity and decreases postprandial hyperglycemia.

  • Image of Acemetacin

    LKT Labs

    Prodrug of indomethacin, NSAID, and COX-1/2 inhibitor used to treat pain and arthritis. It also scavenges ROS and RNS.

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