Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Thr34 of rat DARPP-32
Host: rabbit
Cross Reactivity: (+) rat DARPP-32
Application(s): WB
DARPP-32 is a dopamine and cAMP-regulated phosphoprotein that plays a critical role in the regulation of dopaminergic neurotransmission. The protein inhibits protein phosphatase I when it is phosphorylated on Thr34 and inhibits PKA when phosphorylated on Thr75.