Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Ser301 of rat Raf-1
Host: rabbit
Cross Reactivity: (+) rat Raf-1; expected to react with bovine, canine, chicken, human, mouse, non-human primate, and Xenopus Raf-1
Application(s): WB
Studies have shown that phosphorylation is required for Raf-1 activation. Phosphorylation also down-regulates Raf with two sites participating: Ser301 and Ser642.