Synonyms: Anti-A Disintegrin And Metalloproteinase-10; Anti-Kuzbanian; Anti-MADM
MDL No.: MFCD04040147
Storage: -20C
UNSPSC Code: 12352203
General description: Recognizes the furin cleavage site (58-60 kDa) of ADAM-10. Detects the latent form of the enzyme.
General description: ADAM is a member of the disintegrin and metalloproteinase family of proteins which possess both adhesion and zinc protease functions. ADAM-10 is a sheddase with both a secreted and membrane-bound form. ADAM-10 null mice are embryonically lethal with neural and cardiac defects. Rabbit anti-ADAM-10 antibody can localize human ADAM 10 and does not detect other ADAMs.
Application: Rabbit anti-ADAM-10 antibody has been used for western blot assays.
Immunogen: synthetic peptide corresponding to the prohormone convertase (PC) cleavage site of human ADAM-10.
Physical form: Solution in 0.01 M phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.