Synonyms: GABA Antibody - Monoclonal Anti-GABA antibody produced in mouse; Gaba Antibody Sigma; Anti-gamma-Aminobutyric acid
MDL No.: MFCD00162297
Storage: -20C
UNSPSC Code: 12352203
General description: γ-Aminobutyric acid (GABA) functions as an inhibitory neurotransmitter in the central nervous system. It also functions as a neuromodulator in some peripheral tissues. Additionally, GABA is present in non-nervous tissues and regulates blood pressure, heart rate, respiration, immunomodulation, cell proliferation, protein synthesis and metabolism.Monoclonal Anti-GABA (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. The antibody does not cross react with L-α-aminobutyric acid, L-glutamic acid, L-aspartic acid, glycine, δ-aminovaleric acid, L-threonine, L-glutamine, taurine, putrescine, L-alanine and carnosine. However, weak cross-reaction is observed with β-alanine and ε-aminocaproic acid.
Application: Mouse monoclonal anti-GABA IgG can be used for immunohistochemistry, dot blot (1:100) and indirect ELISA.
Application: Gabaergic cells were identified in the rostal ventrolateral medulla of male Wistar rats by immunofluorescence with mouse monoclonal anti-GABA antibody and colocalized to the angiotensin II type 1 receptor. Sections were incubated in 2% BSA and 0.2% Triton X-100 in 0.01 M PBS for 30 min at 37C to eliminate nonspecific staining.
Immunogen: GABA (gamma-aminobutyric acid) conjugated to BSA
Physical form: Supplied as ascites fluid with 15 mM sodium azide as preservative.
RIDADR: NONH for all modes of transport
WGK Germany: 3
R Codes: 21/22
S Codes: 36/37
IOD Codes: Xn