MGB Alert JC Virus Primer & Probe Mix

Most people infected with JCV are asymptomatic. In those receiving immunosuppressive therapies e.g., transplant recipients, and in the immunocompromised, JCV can cause progressive multifocal leukoencephalopathy (PML), a neurodegenerative disease that is often fatal.¹ The MGB Alert JCV primer mix ASR^§ amplifies, while the probe mix ASR detects, nucleic acids within the VP1 gene in JC virus.

^{1 Pietropaolo V, Prezioso C, Bagnato F, Antonelli G. John Cunningham virus: an overview on biology and disease of the etiological agent of the progressive multifocal leukoencephalopathy. New Microbiol. 2018 Jul;41(3):179-186. https://pubmed.ncbi.nlm.nih.gov/29620790/}

^{§Analyte Specific Reagent. Analytical and performance characteristics are not established.}