Biologically Active Small Molecules Products (6477)

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  • Estrone

    Cayman Chemical
    Item #:
    C836B71-TS

    Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol. Estrone is synthesized from androstenedione by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver. Serum...

  • Prolyl-glycyl-proline Peptide
    Item #:
    C832B09-TS

    Peptide sequence: PGP PGP is a tripeptide molecule and an established biomarker for COPD and CF. PGP functions as a neutrophil chemoattractant and is derived from the proteolytic cleavage of collagen in the extracellular matrix by a multistep cascade.

  • Butylated Hydroxytoluene
    Item #:
    C847N34-TS

    Butylated hydroxytoluene (BHT) is commonly used as a food and cosmetics additive; it exhibits antioxidative and anti-inflammatory activities. BHT may also display neuroprotective benefit, decreasing ethanol-induced brain damage and neurodegeneration and suppressing activation of NF-?B activation and...

  • Bisacodyl

    LKT Labs
    Item #:
    C847M05-TS

    Bisacodyl is a diphenylmethane derivative that exhibits gastrointestinal motility modulating (laxative) activity. Bisacodyl activates macrophages, activating PKC, increasing PGE2 secretion, and downregulating expression of aquaporin 3 channels; it may also inhibit the Na+/K+ ATPase. As a result of...

  • DAPI (hydrochloride)

    Cayman Chemical
    Item #:
    C828E42-TS

    A fluorescent probe which is commonly used to stain DNA and chromosomes for fluorescent microscopy and flow cytometry applications; characterized by ultraviolet (max 358 nm) excitation and blue (max 461 nm) emission wavelengths.

  • 13(S),14(S)-epoxy Fluprostenol isopropyl ester
    Item #:
    C832A74-TS

    A chiral enantiomer of 13,14-epoxy fluprostenol isopropyl ester whose pharmacology has not been studied extensively to date.

  • ABT-737

    LKT Labs
    Item #:
    C848N04-TS

    BH3 mimetic and inhibitor of Bcl-2, Bcl-xl, and Bcl-w. It inhibits growth of acute myelogenous leukemia cells and induces apoptosis and clearance in platelets.

  • 11-dehydro Thromboxane B2 Quant-PAK
    Item #:
    C836D23

    The 11-dehydro TXB2 Quant-PAK has been designed for the convenient, precise quantification of 11-dehydro TXB2 by GC- or LC-MS. It includes a 50 µg vial of 11-dehydro TXB2-d4 and a precisely weighed vial of unlabeled 11-dehydro TXB2, with the precise weight (2-4 mg) indicated on the vial. This...

  • ProClin™ 300

    MilliporeSigma
    Item #:
    C960X93-TS

    ProClin biocides are immediately microstatic upon contact with microbial organisms as a result of their ability to quickly penetrate cell membranes and inhibit specific enzymes crucial to cellular respiration. Multiple specific sites of ProClin toxicity prevent microorganisms from developing high...

  • (+)-Abscisic Acid

    Cayman Chemical
    Item #:
    C834T13-TS

    A plant hormone with diverse roles in disease resistance, plant development, and response to stresses; regulates gene expression and may contribute to epigenetic changes at the chromatin level.

  • Fludarabine

    Cayman Chemical
    Item #:
    C830L19-TS

    A nuclesoside analog that disrupts DNA synthesis in blood cells; effective in a number of animal tumor systems including LI210 leukemia, CD8F mammary adenocarcinoma, P388 leukemia, and human LX-1 lung tumor xenograft and displays anticancer activity against human hematological malignancies in vivo.

  • Butoconazole Nitrate
    Item #:
    C847N86-TS

    Butoconazole is an imidazole derivative that exhibits antifungal/antimycotic and anti-parasitic activities; it likely inhibits 14-a demethylase. Butoconazole displays particularly effective antimicrobial activity against species of Candida, Saccharomyces, and Trichomonas. Grade: ≥98%

  • (+)-Catechin

    LKT Labs
    Item #:
    C847Q81-TS

    Catechin is a flavanol originally found in Camilla and other plant sources; it exhibits antioxidative, anti-aging, anti-atherosclerotic, anti-ulcerative, neuroprotective, neuromodulatory, anticancer chemotherapeutic, and chemopreventive activities. Catechin increases life span in Caenorhabditis...

  • SureLight® P3

    Cayman Chemical
    Item #:
    C817W34

    Applications: This proprietary dye can be used in prompt fluorescent detection, microplate applications, flow cytometry and protein microarrays. Because its absorption and emission profile is similar to Cy5, it can be used in many of the same applications, however, it is 200 times brighter....

  • Mn(III)TMPyP

    Cayman Chemical
    Item #:
    C789G42-TS

    Mn(III)TMPyP is a cell-permeable SOD mimic and peroxynitrite decomposition catalyst. The rate constants for superoxide dismutation and peroxynitrite decomposition are 3.9 x 107 M−1s−1 and ~2 x 106 M−1s−1, respectively.

  • NO-Losartan A

    Cayman Chemical
    Item #:
    C836B55-TS

    Angiotensin II is a hormone that plays an important role in regulating blood pressure. Elevated levels of angiotensin II are implicated in inducing and maintaining hypertension, and also in the development of atherosclerosis. Both of these effects are mediated by the angiotensin II type 1 (AT1)...

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