Acetic anhydride participates in the Friedel-Craft′s intramolecular cyclization reaction of cyclopropyl ketones to afford the tetralones. It has been reported to promote the Knoevenagel condensation of various aldehydes and activated methylene compounds.
Molecular Formula: C4H6O3
Molecular Weight: 102.09
Linear Structural Formula: (CH3CO)2O
MDL Number: MFCD00008705
Purity: >=99%
Melting Point: -73 C (lit.)
Density: 1.08 g/mL (lit.)
Refractive Index: n20/D 1.390 (lit.)
Application: Acetic anhydride was used in the following studies:
•Lipozyme TL IM (commercial immobilized lipase from Thermomyces lanuginosus) catalyzed acetylation of essential clove oil.
•As acetyl donor to investigate the lipase catalyzed acetylation of nanofibrillated cellulose (NFC).
•Synthesis of N-substituted pyrazolines.
•Acetylation of Barnyardgrass (Echinochloa crus-galli) starch.
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RTECS: AK1925000
RIDADR: UN 1715 3(8) / PGII
WGK Germany: 1
Flash Point(F): 120.2 F
Flash Point(C): 49 C
R Codes: 10-20/22-34
S Codes: 26-36/37/39-45
IOD Codes: C
Symbol: GHS02, GHS05, GHS06
Signal Word: Danger
Hazard Statements: H226-H302-H314-H330
Precautionary statements: P210-P260-P280-P304 + P340 + P310-P305 + P351 + P338-P370 + P378