Aniline, ACS reagent, >=99.5%

CAS Number: 62-53-3

Formula: C6H7N

Formula Weight: 93.13

Linear Formula: C6H5NH2

MDL No.: MFCD00007629

Purity: >=99.5%

Boiling Point: 184 C(lit.)

Melting Point: -6 C (lit.)

Density: 1.022 g/mL at 25 C(lit.)

Refractive Index: n20/D 1.586(lit.)

Beilstein Registry Number: 605631

EC Number: 200-539-3

UNSPSC Code: 12352100

Application: Aniline is an aromatic primary amine that may be used as a reactant in the synthesis of organic intermediates such as 3-chloro-N-phenyl-pyridin-2-amine, (Z)-methyl 3-(phenylamino)but-2-enoate, 2-iodo-N-phenylbenzamide, 2,4-dichloroquinoline and N-(2-propynyl)aniline.

Biochem/physiol Actions: The acute toxicity of aniline involves its activation in vivo to 4-hydroxyaniline and the formation of adducts with hemoglobin. In erythrocytes, this is associated with the release of iron and the accumulation of methemoglobin and the development of hemolytic anemia and inflammation of the spleen. Tumor formation is often observed in the spleen on prolonged administration.

Physical properties: Material darkens in storage to reddish-brown with no loss in purity.