Synonyms: Actinomycin C1; Actinomycin IV; Dactinomycin
Formula: C62H86N12O16
Formula Weight: 1255.42
CAS No.: 50-76-0
Purity: ≥95% (HPLC)
Storage Temperature: 2-8°C
Biochem/physiol Actions: An antineoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymerase which interferes with DNA-dependent RNA synthesis. Induces apoptosis. Potent antitumor agent. For cell culture applications, actinomycin D is used as a selection agent and is used in banding techniques to differentiate between different regions of chromosomes.
Protocols & Applications: Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
Assay: ≥95% (HPLC)
Biological Source: from Streptomyces sp.
Color: red, powder
MP: 251-253
Solubility: ethanol, DMSO: soluble
Storage Temp.: 2-8°C