Synonyms: DMSO
Molecular Formula: C2H6OS
Molecular Weight: 78.13
Linear Structural Formula: (CH3)2SO
MDL Number: MFCD00002089
Purity: >=99.5%
Melting Point: 16-19 C (lit.)
Density: 1.100-1.104 g/mL at 25 C (relative density (EP)); 1.10 g/mL (lit.)
Refractive Index: n20/D 1.478-1.479; n20/D 1.479 (lit.)
Application: Dimethyl sulfoxide has been used:
•for the dissolution of tetramethylrhodamine dye, which is used as fluorophore for fluorescence in- situ hybridization (FISH) experiments
•as a control in indirect immunofluorescent assay (IFA) of swine testicular (ST) cells
•for the suspension and separation of buccal cells
•a polar aprotic solvent used in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs.
Biochem Physiol Actions: Dimethyl sulfoxide (DMSO) is a low molecular weight, less hydrophilic and a freely permeable cryoprotectant. It is a polar aprotic solvent used in polymerase chain reactions (PCR) and as a cryoprotectant and vitrification agent for the preservation of cells, tissues and organs.
Other Notes: For information on dimethyl sulfoxide miscibility, please visit the following link:Dimethyl Sulfoxide Miscibility/Immiscibility Table
Autoignition Temp.: 573°F
BP: 189°C(lit.)
Density: 1.10 g/mL(lit.)
Expl. Lim.: 42 %, 63°F
Impurities: ≤0.2% water (Karl Fischer, EP)
MP: 16-19°C(lit.)
Refractive Index: n20/D 1.479(lit.)
Suitability: meets EP testing specifications
UV Absorption: λ: 285 nm Amax: ≤0.20
Vapor Density: 2.7 (vs air)
Vapor Pressure: 0.42 mmHg ( 20°C)