Synonyms: N-(4-Acetylphenyl)-3-(5-ethyl-2-furanyl)-2-propenamide
Molecular Formula: C17H17NO3
Molecular Weight: 283.32
Linear Structural Formula: C17H17NO3
Purity: >=98% (HPLC)
Storage: 2-8C
Application: Heclin has been used as a HECT-type ubiquitin E3 ligase inhibitor in human embryonic kidney (HEK293) cells. It has also been used to test its effect on dandelion-induced chloride channel protein (ClC-Ka) inhibition in HEK293 cells and fibroblast-like COS-7 cell line.
Biochem Physiol Actions: Heclin is not effective in inhibiting E1 or E2 proteins.