Microglia are the primary immune cells of the central nervous system (CNS), and account for 10-15% of all cells found within the brain. Microglial cells play an important role in maintaining the health of the CNS by the removal of pathogens, infectious agents and damaged cells through phagocytosis. Microglial cells have also been extensively studied for their harmful roles in a variety of neurodegenerative disease including Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.
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