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Synonyms: Ru2Cl2(p-cymene) (HCOO)2 . HCOONa; Ru2Cl2(p-cymene) (HCOO)3Na; Sodium eta-6-p-cymene dichloro diruthenium (II, III) triformato complex
Molecular Formula: C13H17Cl2NaO6Ru2
Molecular Weight: 565.31
Linear Structural Formula: C13H17Cl2NaO6Ru2
Melting Point: 247.8 C
Storage: 2-8C
Application: MCAT-53 is a recyclable ruthenium-containing catalyst for C-C coupling reactions in aqueous conditions. In contrast to Pd-catalyzed reactions, MCAT-53 achieves C-H-activated C-C coupling in water under ligand-free conditions, requiring no co-solvent, surfactant, or additional steps for activation. Bench- and air-stable, MCAT-53 will find wide utility in cost-effective and greener alternatives in pharmaceutical and manufacturing processes. This water-friendly catalyst is offered in collaboration with Chicago Discovery Solutions.The catalyst has been successfully employed to synthesize a key intermediate of anacetrapib as a single regioisomer.
Legal Information: MCAT-53 is a trademark of Chicago Discovery Solutions LLC
Other Notes: Arene Ruthenium Catalyst MCAT-53 for the Synthesis of Hetero-biaryl Compounds in Water through Aromatic C-H bond ActivationMCAT-53(TM): A Green Ruthenium Catalyst for Cross-Coupling & C-H Activation