Synonyms: 5'-(2-Hydroxyphenyl)-1-methylspiro[3H-indole-3,2'(3'H)-[1,3,4]thiadiazol]-2(1H)-one; Manganese-Extracting Small Molecule; VU0028386
Molecular Formula: C16H13N3O2S
Molecular Weight: 311.36
Linear Structural Formula: C16H13N3O2S
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: MESM is a cell penetrant and non-toxic selective manganese ionophore that potently facilitates of manganese export from cells. MESM can be used to rapidly extract and quantify cellular manganese content in a non-lethal and selective MESMER (Manganese-Extracting Small Molecule Estimation Route) assay. MESM does not impacted Fura-2 AM fluorescence.