c-Myc is a transcription factor which is over-expressed in a wide range of cancers.
Synonyms: Anti-c-Myc
Storage: -20C
Application: Monoclonal anti-c-Myc antibody produced in mouse has been used for Western blotting and immunohistochemistry.Monoclonal Anti-c-Myc antibody has also been used in:
•the detection of horseradish peroxidase conjugate in phosphate buffered saline tween-20 (PBST) and 65-kDa mannoprotein (MP65) Dabs
•immunoblotting
•immunoprecipitation
•biochemical and histological studies
Biochem Physiol Actions: c-Myc is a regulator of the cell cycle and aids in the growth of tumors in the liver. Translocations in the gene encoding it have been shown to be linked to Burkitt lymphoma. It has been studied that c-Myc targets many protein-coding genes which enhances the oncogenic properties of c-Myc.