Synonym: 2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid, Taurodeoxycholic acid sodium salt hydrate
CAS Number: 207737-97-1
Linear Formula: C26H44NO6SNa
Molecular Weight: 521.69 (anhydrous basis)
Beilstein Registry Number: 3901204
MDL Number: MFCD00149238
PubChem Substance ID: 24899897
Application
Bile salt-related, anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins.
Sodium tauroursodeoxycholate has been used in a study to assess short-term feedback regulation of bile salt uptake in rodent liver. It has also been used in a study to investigate its potential to resolve endoplasmic reticulum (ER) stress in intestinal epithelial cells. It is also used for isolation of membrane proteins including inner mitochondrial membrane proteins.
General Description
Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.
Description: anionic
Product Line: BioXtra
Assay: ≥97% (TLC)
Mol. Wt.: micellar avg mol wt 3100
Aggregation Number: 6
Impurities: ≤0.002% Phosphorus (P); ≤0.1% Insoluble matter
CMC: 1-4 mM(20-25°C)
MP: 168 °C (dec.)(lit.)
Solubility: H2O: soluble0.5 M, clear, colorless to faintly yellow
Anion Traces: chloride (Cl-): ≤0.5%; sulfate (SO42-): ≤0.05%
Cation Traces: Al: ≤0.0005%; Ca: ≤0.005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.01%; Mg: ≤0.005%; NH4+: ≤0.05%; Pb: ≤0.001%; Zn: ≤0.0005%