Fluid A (peptone water) is used for diluting or rinsing when performing sterility testing.
Pharmaceuticals, biologicals, medical devices or any material claiming to be sterile must be tested for sterility according to the procedures described in the compendia.1,2 Sterility testing is performed using the membrane filtration or direct testing methods, depending upon sample type and size. Fluid A and Fluid D are used for diluting or rinsing when performing sterility testing. These fluids aid in the complete rinsing of the membrane filter apparatus and are not toxic to microorganisms.
Fluid A and Fluid D contain peptic digest of animal tissue, which provides a source of nitrogen for bacteria.
Fluid A and Fluid D are provided as prepared, ready-to-use diluents in a variety of bottle sizes and closures. Consult appropriate references for detailed information and recommended procedures.
Appearance: Nearly colorless, clear solution
Reaction of Solution at 25°C: pH 7.1 ± 0.2
Meets United States Pharmacopeia (USP) performance specifications.