The MagDEA Dx LV is a magnetic bead-based chemistry for extracting total nucleic acids from whole blood. Sample starting volume is 5mL , but smaller volumes can be used by bringing the sample volume up to 5 mL with PBS. The extraction process includes sample lysis, proteinase K digestion, magnetic bead adsorption, washing and elution for high-yield and high-purity DNA/RNA recovery with extremely low guanidinium salt carry over. The reagent cartridge is self-contained providing all necessary chemistry and waste collection.