Pure•SAL™ was developed for the controlled and standardized collection of RNA or protein biomarkers from oral fluid specimens for subsequent stabilization and analysis in life science and research applications.
The Pure•SAL™ Oral Specimen Collection Kit provides a simple non-invasive and rapid platform for isolating “liquid biopsy” specimens including cell free DNA, cell free RNA, exosomes, or proteins in a single step. The harvested, purified saliva specimen is stabilized if required and available for downstream PCR, genotyping, sequencing, proteomics and other applications, depending upon the desired results.
Principles of the Kit
Pure•SAL™ uses a highly absorbent pad to collect saliva, which also acts to remove a high percentage of mucinous material that can cause interference with downstream assays. The Sample is subsequently purified further by expressing the sample through the compression tube of the device containing a proprietary filtration medium that removes additional interferants and large molecules. The purified sample is then directed into a standard collection tube and is stabilized independently for immediate use or stored for long periods of time pending analysis.