Qkine Ltd.
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Human PDGF-AA (platelet derived growth factor AA) protein is a homodimer of PDGF-A peptide chains. This protein is a potent mitogen involved in embryogenesis.1 PDGF-AA is commonly used to differentiate human pluripotent stem cell (hPSC)-derived neural pro
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Macrophage Colony-Stimulating Factor (M-CSF)
Qkine Ltd.Macrophage colony-stimulating factor (M-CSF) is a cytokine that regulates the survival, proliferation, differentiation, and functional activation of monocytes, such as macrophages and dendritic cells. Various cells produce and release M-CSF, such as endot
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Recombinant human neurotrophin 3 (NT3) protein is part of the NGF family of neurotrophic factors. NT-3 promotes differentiation and survival of specific neuronal subpopulations in both the central nervous system and peripheral nervous system. This growth
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Human PDGF-BB (platelet derived growth factor BB) protein is a homodimer of PDGF-B peptide chains. PDGF is a potent mitogen involved in embryogenesis.PDGF-BB is used in neuronal differentiation2 and treatment of periodontal and orthopedic bone defects and
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Recombinant Human HGF Protein
Qkine Ltd.Recombinant human HGF protein is a potent, high purity NK1 isoform of human hepatocyte growth factor (HGF) that promotes efficient differentiation of human iPSCs to hepatocyte-like cells at just 10 ng/ml with highly homogeneous expression of the hepatic m
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Recombinant human R-spondin 1 protein (RSPO1) is the prototypic member of the R-spondin family and is used to potentiate Wnt signalling in many organoid culture systems including intestinal and tumor (cancer) organoid culture. R-spondin 1 is also required
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Mouse/Rat Noggin
Qkine Ltd.Mouse/rat noggin is a bone morphogenetic protein (BMP) family antagonist used in the culture of intestinal, pancreatic, lung and tumor-derived organoids, maintenance of undifferentiated embryonic stem cells and for stem cell differentiation into neural an
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Human Glial cell line-derived neurotrophic factor (GDNF) protein supports the maintenance and differentiation of numerous types of neurons including dopaminergic neurons. GDNF is used to differentiate human pluripotent stem cell into neurons1 and in pluri
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Human LIF (leukemia inhibitory factor) protein suppresses the differentiation of murine embryonic stem cells (ESCs) and is widely used in ESC and iPSC culture.Qkine human LIF protein is high purity and animal and carrier-protein free for reproducible resu
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Granulocyte colony-stimulating factor (G-CSF) is a member of the hematopoietic growth factor family which plays a crucial role in the proliferation, differentiation, and maturation of committed progenitor cells to granulocytes, such as neutrophils. G-CSF
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Recombinant Human R-Spondin 1 LR5 Protein
Qkine Ltd.Recombinant human r-spondin 1 LR5 protein is engineered to act as a high affinity ligand for the LGR5 receptor. In epithelial tissues LGR5 marks the stem cell population. This engineered protein, R-spondin 1 LR5, activates wnt signalling only in the LGR
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Recombinant bovine/porcine FGF2 protein 145 aa (bFGF/basic FGF) for the development of species-specific bovine (cow) and porcine (pig) cellular agriculture protocols and veterinary research applications. Used in comparative cell culture media optimization
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Porcine EGF
Qkine Ltd.Porcine EGF is an essential growth factor belonging to the Epidermal Growth Factor family that stimulates the proliferation and differentiation of cells. It is used for the differentiation of induced pluripotent stem cells (iPSCs) and embryonic stem cells
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Human FGF2 /bFGF Protein (145 aa)
Qkine Ltd.Human FGF2 /bFGF protein (145 aa) is our gold-standard and recommended FGF2 / bFGF protein for induced pluripotent stem cell (iPSC) and embryonic stem cells (ESC) maintenance, and induced pluripotent and mesenchymal stem cells proliferation and differenti
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Recombinant human vascular endothelial growth factor 165 (also known as VEGF165/ VEGF-165/ VEGF-A/ VEGF165) protein is widely used in culturing primary endothelial cells (ECs), such as human umbilical vein endothelial cells (HUVEC), under serum-free condi
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Recombinant Human FGF2 Protein (154 aa)
Qkine Ltd.Recombinant human FGF2 protein (154 aa) is a highly bioactive, long–form of human fibroblast growth factor 2 protein. FGF-2 protein is used to support the maintenance of human embryonic stem cells and proliferation and differentiation of induced pluripote
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Human FGF-4 Protein
Qkine Ltd.Human FGF-4 protein is used for the proliferation and differentiation of embryonic and induced-pluripotent and tissue (mesenchymal) stem cells and promotes neural stem cell proliferation. FGF-4 is an important component of cardiac, intestinal and other o
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Human TGF-ß3 Protein
Qkine Ltd.Human TGF-ß3 protein is a member of the Transforming Growth Factor family, a family involved in regulating cell survival, proliferation and differentiation.1 TGF-ß3 is used in human pluripotent stem cell maintenance medias, such as B8 media.2 High purity
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Human OSM Protein (Oncostatin M)
Qkine Ltd.Human OSM protein (oncostatin M) is used in the differentiation of human pluripotent stem cells into hepatocyte-like cells. OSM also plays roles in osteogenesis and neurogenesis, and is an important regulator of the hematopoietic stem cell niche in the bo
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BMP-2 Protein (Bone Morphogenetic Protein 2)
Qkine Ltd.Human/mouse/rat/bovine/porcine BMP-2 protein (bone morphogenetic protein 2) protein is member of the TGFß family and a key regulator of embryogenesis and potent differentiation factor of embryonic stem cells (ESC) and induced pluripotent stem cells (iPSC)
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Human KGF Protein (FGF-7)
Qkine Ltd.Human KGF protein (FGF-7) is a member of the FGF family secreted by mesenchymal cells and has a paracrine effect on neighbouring epithelial cells.1 KGF protein is used in the culture of lung, breast, liver, and bladder organoids.2 In vivo, KGF is involved
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FGF10 Protein
Qkine Ltd.Human/rat/porcine/bovine FGF10 protein promotes lung organoid formation and induces branching morphology. FGF10 protein is used widely in organoid culture, embryonic stem cell (ESC) and induced-pluripotent stem cell (iPSC) differentiation, and for the st
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Fibroblast Growth Factor 8a (FGF-8a)
Qkine Ltd.Fibroblast growth factor 8a (FGF-8a) is a member of the FGF family and plays a key role in the regulation of embryogenesis, cellular proliferation, differentiation, and migration. FGF8a is often used for the differentiation of induced pluripotent stem cel
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Ciliary Neurotrophic Factor (CNTF)
Qkine Ltd.Ciliary Neurotrophic Factor (CNTF) is a member of the IL-6 family of cytokines. CNTF plays a crucial role in developing and maintaining the nervous system, in particular the optic nervous system. It promotes the maintenance, differentiation, and survival
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Human R-Spondin 3 Protein
Qkine Ltd.Human R-spondin 3 protein potentiates Wnt signalling in and has been shown to function in crypt regeneration in the intestine and control stem cell and progenitor cell behaviour during kidney development. R-spondin 3 is used alongside R-spondin 1 in intes
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Recombinant Bovine HGF Protein
Qkine Ltd.Recombinant bovine HGF protein is a potent, high-purity NK1 isoform of bovine hepatocyte growth factor (HGF). Bovine HGF differs from human HGF at several key amino acid residues that are predicted to affect bioactivity and receptor binding. Use of spe
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Zebrafish FGF-2 Protein
Qkine Ltd.Zebrafish FGF-2 protein (bFGF/basic FGF) has been used extensively to support the maintenance and proliferation of human and mouse induced pluripotent (iPSC) and embryonic stem cells (ESC); used in the original Ludwig et al feeder-free culture of embryoni
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Recombinant Mouse FGF2 Protein
Qkine Ltd.Recombinant mouse FGF2 protein/ bFGF is an important factor in the maintenance of mouse epiblast-derived stem cells (EpiSC). Mouse naïve pluripotency is maintained by LIF, BMP4, and Wnt signalling pathways. However, the primed state of pluripotency in mou
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Gremlin 1 Protein
Qkine Ltd.Human/bovine/porcine Gremlin 1 protein is a BMP-inhibitor present in the natural intestinal niche and provides an alternative to Noggin for optimisation of intestinal organoid culture and iPSC differentiation. Qk015 has been optimized by our experts for e
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Human GDF15 (growth differentiation factor 15) protein is a member of the TGFß family and subject of intense interest as a marker of cellular stress and for its role in metabolism, cancer and pregnancy. Human GDF15 also is functional in mouse studies. Th
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Follistatin-resistant activin A protein (FRACTA) has been engineered to prevent binding to the natural inhibitor, follistatin. Activin A activity protein is regulated in vivo by follistatin, a high-affinity inhibitor; follistatin accumulates in stem cell
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Human Noggin
Qkine Ltd.Human noggin is a bone morphogenetic protein (BMP) family antagonist used in the culture of intestinal, pancreatic, lung and tumor-derived organoids, maintenance of undifferentiated embryonic stem cells and for stem cell differentiation into neural and mi
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